Right off the bat, we're greeted with a rather concise set of procedures. The containment itself is briefly handled in order to get to the juicy bit (namely, cross-testing! yay!) quickly, but more importantly:
Subjects should be sedated prior to strangulation with SCP-2486.
No further elaboration or hemming on, just a very direct and odd detail that is sure to stick in one's mind. If the mention of cross-testing doesn't do it for you, this alone is an excellent hook.
Don't let your SCProcedures go to waste. They aren't just important in-universe, they're a tool that you as an author can use to draw readers in, by setting up certain expectations, or creating mystery.
The basic anomaly/effect is pretty interesting all its own, and there's one small important detail that not only averts cliche, but is used to great effect in the experiment log.
Subjective assessments and descriptions of SCP-2486-A frequently incorporate imagery
Emphasis mine.
"He still looks like an asshole."
XD Awesome! I laughed my ass off here. Oftentimes with memes/compulsions/various mind-affecting stuff, everyone exposed/affected will basically act the same, and that gets boring rather quickly. Try to consider whether you could benefit from limiting your anomaly's mind-based affects, so you can show how different people react to it.
After all this? Cross-testing. Notice, that at no point do the tests spiral out of control, killing a ton of researchers or destroying sites. Neither does it devolve into an…er…SKIP measuring contest, 'pitting' the SCP against others in an attempt to Worf the SCPs it links to. It simply presents itself intermingled with SCPs from every series, and has them interact in an interesting way. In doing this, it actively avoids all (most of?) the tropes that turn people off to cross-testing in the first place.
The tests are well done. They stay true to their sources; and offer a selection ranging across every series, which is wonderful wiki-walk-fuel. Each one is unique and interesting, and not one test regurgitates information we already have (an issue I've seen in quite a few drafts). This is cross-testing done right.
Overall, this entry gave me some 'classic S1' vibes, and is a prime example of why I'm excited for the Grand Crosslinking.